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Incomplete Penetrance and Variable Expressivity: From Clinical Studies to Population Cohorts

The same genetic variant found in different individuals can cause a range of diverse phenotypes, from no discernible clinical phenotype to severe disease, even among related individuals. Such variants can be said to display incomplete penetrance, a binary phenomenon where the genotype either causes...

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Detalles Bibliográficos
Autores principales:	Kingdom, Rebecca, Wright, Caroline F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380816/ https://www.ncbi.nlm.nih.gov/pubmed/35983412 http://dx.doi.org/10.3389/fgene.2022.920390

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