Cargando…

Small Molecules Targeting SARS-CoV-2 Spike Glycoprotein Receptor-Binding Domain

[Image: see text] The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the coronavirus disease 2019 (COVID-19) pandemic. Several variants of SARS-CoV-2 have emerged worldwide. These variants show different transmissibility infectivity due to mutations in the viral spike (S) gl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rodríguez, Yoel, Cardoze, Scarlet Martínez, Obineche, Onyinyechi W., Melo, Claudia, Persaud, Ashanna, Fernández Romero, José A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380817/ https://www.ncbi.nlm.nih.gov/pubmed/35991504 http://dx.doi.org/10.1021/acsomega.2c00844

Ejemplares similares

Crystallization and Structural Determination of the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein
por: Zhou, Haixia, et al.
Publicado: (2019)

Site-specific characterization of SARS-CoV-2 spike glycoprotein receptor-binding domain
por: Antonopoulos, Aristotelis, et al.
Publicado: (2020)

A Cryptic Site of Vulnerability on the Receptor Binding Domain of the SARS-CoV-2 Spike Glycoprotein
por: Joyce, M. Gordon, et al.
Publicado: (2020)

Screening, simulation, and optimization design of small molecule inhibitors of the SARS-CoV-2 spike glycoprotein
por: Sun, Chuancai, et al.
Publicado: (2021)

Heme binding to the SARS-CoV-2 spike glycoprotein
por: Freeman, Samuel L., et al.
Publicado: (2023)

Structural Definition of a Unique Neutralization Epitope on the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein
por: Zhang, Senyan, et al.
Publicado: (2018)

Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
por: Yuan, Yuan, et al.
Publicado: (2017)

Implications for SARS-CoV-2 Vaccine Design: Fusion of Spike Glycoprotein Transmembrane Domain to Receptor-Binding Domain Induces Trimerization
por: Azad, Taha, et al.
Publicado: (2020)

Immunoglobulin yolk targeting spike 1, receptor binding domain of spike glycoprotein and nucleocapsid of SARS-CoV-2 blocking RBD-ACE2 binding interaction
por: Eka Saputri, Meliana, et al.
Publicado: (2022)

Computer aided prediction and identification of potential epitopes in the receptor binding domain (RBD) of spike (S) glycoprotein of MERS-CoV
por: ali, Mohammad Tuhin, et al.
Publicado: (2014)

SARS-CoV-2 beta variant substitutions alter spike glycoprotein receptor binding domain structure and stability
por: Moss, Daniel L., et al.
Publicado: (2021)

Crystal structure of the receptor binding domain of the spike glycoprotein of human betacoronavirus HKU1
por: Ou, Xiuyuan, et al.
Publicado: (2017)

In silico screening of known small molecules to bind ACE2 specific RBD on Spike glycoprotein of SARS-CoV-2 for repurposing against COVID-19
por: BR, Bharath, et al.
Publicado: (2020)

Assessment of the binding interactions of SARS-CoV-2 spike glycoprotein variants
por: Raghu, Deepa, et al.
Publicado: (2022)

Characterization of Phytochemicals in Ulva intestinalis L. and Their Action Against SARS-CoV-2 Spike Glycoprotein Receptor-Binding Domain
por: Kulkarni, Seema A., et al.
Publicado: (2021)

Novel Small-Molecule Inhibitors of the SARS-CoV-2 Spike Protein Binding to Neuropilin 1
por: Kolarič, Anja, et al.
Publicado: (2022)

Identification of a SARS-like bat coronavirus that shares structural features with the spike glycoprotein receptor-binding domain of SARS-CoV-2
por: Fraguas Bringas, Conchita, et al.
Publicado: (2020)

Identifying Hotspots in Binding of SARS-CoV-2 Spike Glycoprotein and Human ACE2
por: Mendis, Jenny, et al.
Publicado: (2021)

The binding of heparin to spike glycoprotein inhibits SARS-CoV-2 infection by three mechanisms
por: Paiardi, Giulia, et al.
Publicado: (2021)

The Sialoside-Binding Pocket of SARS-CoV-2 Spike Glycoprotein Structurally Resembles MERS-CoV
por: Awasthi, Mayanka, et al.
Publicado: (2020)

Structure and binding properties of Pangolin-CoV spike glycoprotein inform the evolution of SARS-CoV-2
por: Wrobel, Antoni G., et al.
Publicado: (2021)

Structural definition of a neutralization epitope on the N-terminal domain of MERS-CoV spike glycoprotein
por: Zhou, Haixia, et al.
Publicado: (2019)

Emergence of a recurrent insertion in the N-terminal domain of the SARS-CoV-2 spike glycoprotein
por: Gerdol, Marco, et al.
Publicado: (2022)

SARS-CoV-2 Omicron spike glycoprotein receptor binding domain exhibits super-binder ability with ACE2 but not convalescent monoclonal antibody
por: Omotuyi, Olaposi, et al.
Publicado: (2022)

Domain-based small molecule binding site annotation
por: Snyder, Kevin A, et al.
Publicado: (2006)

Mapping small molecule binding data to structural domains
por: Kruger, Felix A, et al.
Publicado: (2012)

Dose-Related Aberrant Inhibition of Intracellular Perforin Expression by S1 Subunit of Spike Glycoprotein That Contains Receptor-Binding Domain from SARS-CoV-2
por: Huang, Chun-Fu, et al.
Publicado: (2021)

Label-Free Detection of the Receptor-Binding Domain of the SARS-CoV-2 Spike Glycoprotein at Physiologically Relevant Concentrations Using Surface-Enhanced Raman Spectroscopy
por: Sarychev, Andrey K., et al.
Publicado: (2022)

Homology Modeling and Molecular Dynamics-Driven Search for Natural Inhibitors That Universally Target Receptor-Binding Domain of Spike Glycoprotein in SARS-CoV-2 Variants
por: Ovchynnykova, Olha, et al.
Publicado: (2022)

Identifying Small‐Molecule Binding Sites for Epigenetic Proteins at Domain–Domain Interfaces
por: Bowkett, David, et al.
Publicado: (2018)

Optimized Pseudotyping Conditions for the SARS-COV-2 Spike Glycoprotein
por: Johnson, Marc C., et al.
Publicado: (2020)

Expression, Glycosylation, and Modification of the Spike (S) Glycoprotein of SARS CoV
por: Shen, Shuo, et al.
Publicado: (2007)

Controlling the SARS-CoV-2 Spike Glycoprotein Conformation
por: Henderson, Rory, et al.
Publicado: (2020)

Controlling the SARS-CoV-2 spike glycoprotein conformation
por: Henderson, Rory, et al.
Publicado: (2020)

Glycoprotein molecular dynamics analysis: SARS-CoV-2 spike glycoprotein case study
por: Coutinho, João Victor Paccini, et al.
Publicado: (2022)

Systemic effects of missense mutations on SARS-CoV-2 spike glycoprotein stability and receptor-binding affinity
por: Teng, Shaolei, et al.
Publicado: (2020)

The SARS‐CoV‐2 Spike Glycoprotein Directly Binds Exogeneous Sialic Acids: A NMR View
por: Unione, Luca, et al.
Publicado: (2022)

The spike glycoprotein of SARS-CoV-2: A review of how mutations of spike glycoproteins have driven the emergence of variants with high transmissibility and immune escape
por: Souza, Pedro F.N., et al.
Publicado: (2022)

Interaction of Epigallocatechin Gallate and Quercetin with Spike Glycoprotein (S-Glycoprotein) of SARS-CoV-2: In Silico Study
por: Alavi, Mehran, et al.
Publicado: (2022)

Translocating Peptides of Biomedical Interest Obtained from the Spike (S) Glycoprotein of the SARS-CoV-2
por: Henao, Maria C., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_36665btcdfag416v38pmpfsim0