Cerebellar Structure and Function in Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition characterized by early-onset repetitive behaviors, restricted interests, sensory and motor difficulties, and impaired social interactions. Converging evidence from neuroimaging, lesion and postmortem studies, and rodent m...

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Detalles Bibliográficos
Autores principales: Bloomer, Bess F., Morales, Jaime J., Bolbecker, Amanda R., Kim, Dae-Jin, Hetrick, William P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380863/
https://www.ncbi.nlm.nih.gov/pubmed/35978711
http://dx.doi.org/10.20900/jpbs.20220003
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author Bloomer, Bess F.
Morales, Jaime J.
Bolbecker, Amanda R.
Kim, Dae-Jin
Hetrick, William P.
author_facet Bloomer, Bess F.
Morales, Jaime J.
Bolbecker, Amanda R.
Kim, Dae-Jin
Hetrick, William P.
author_sort Bloomer, Bess F.
collection PubMed
description Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition characterized by early-onset repetitive behaviors, restricted interests, sensory and motor difficulties, and impaired social interactions. Converging evidence from neuroimaging, lesion and postmortem studies, and rodent models suggests cerebellar involvement in ASD and points to promising targets for therapeutic interventions for the disorder. This review elucidates understanding of cerebellar mechanisms in ASD by integrating and contextualizing recent structural and functional cerebellar research.
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spelling pubmed-93808632022-08-16 Cerebellar Structure and Function in Autism Spectrum Disorder Bloomer, Bess F. Morales, Jaime J. Bolbecker, Amanda R. Kim, Dae-Jin Hetrick, William P. J Psychiatr Brain Sci Article Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition characterized by early-onset repetitive behaviors, restricted interests, sensory and motor difficulties, and impaired social interactions. Converging evidence from neuroimaging, lesion and postmortem studies, and rodent models suggests cerebellar involvement in ASD and points to promising targets for therapeutic interventions for the disorder. This review elucidates understanding of cerebellar mechanisms in ASD by integrating and contextualizing recent structural and functional cerebellar research. 2022 2022-06-27 /pmc/articles/PMC9380863/ /pubmed/35978711 http://dx.doi.org/10.20900/jpbs.20220003 Text en https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms and conditions of Creative Commons Attribution 4.0 International License.
spellingShingle Article
Bloomer, Bess F.
Morales, Jaime J.
Bolbecker, Amanda R.
Kim, Dae-Jin
Hetrick, William P.
Cerebellar Structure and Function in Autism Spectrum Disorder
title Cerebellar Structure and Function in Autism Spectrum Disorder
title_full Cerebellar Structure and Function in Autism Spectrum Disorder
title_fullStr Cerebellar Structure and Function in Autism Spectrum Disorder
title_full_unstemmed Cerebellar Structure and Function in Autism Spectrum Disorder
title_short Cerebellar Structure and Function in Autism Spectrum Disorder
title_sort cerebellar structure and function in autism spectrum disorder
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380863/
https://www.ncbi.nlm.nih.gov/pubmed/35978711
http://dx.doi.org/10.20900/jpbs.20220003
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