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Protective effect of Astragaloside IV on chronic intermittent hypoxia-induced vascular endothelial dysfunction through the calpain-1/SIRT1/AMPK signaling pathway

Vascular endothelial dysfunction (VED) is linked with the pathogenesis of obstructive sleep apnea (OSA) comorbidities, such as cardiovascular disease. Astragaloside IV (As-IV) has exhibited significant improvement for endothelial dysfunction. Nonetheless, the protective mechanism is not clear. There...

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Detalles Bibliográficos
Autores principales:	Zhao, Fang, Meng, Yan, Wang, Yue, Fan, Siqi, Liu, Yu, Zhang, Xiangfeng, Ran, Chenyang, Wang, Hongxin, Lu, Meili
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381017/ https://www.ncbi.nlm.nih.gov/pubmed/35983375 http://dx.doi.org/10.3389/fphar.2022.920977

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