Cargando…

VPRBP Functions Downstream of the Androgen Receptor and OGT to Restrict p53 Activation in Prostate Cancer

Androgen receptor (AR) is a major driver of prostate cancer initiation and progression. O-GlcNAc transferase (OGT), the enzyme that catalyzes the covalent addition of UDP-N-acetylglucosamine (UDP-GlcNAc) to serine and threonine residues of proteins, is often highly expressed in prostate cancer with...

Descripción completa

Detalles Bibliográficos
Autores principales: Poulose, Ninu, Forsythe, Nicholas, Polonski, Adam, Gregg, Gemma, Maguire, Sarah, Fuchs, Marc, Minner, Sarah, Sauter, Guido, McDade, Simon S., Mills, Ian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381113/
https://www.ncbi.nlm.nih.gov/pubmed/35348747
http://dx.doi.org/10.1158/1541-7786.MCR-21-0477

Ejemplares similares