Suppression of Endothelial Cell FAK Expression Reduces Pancreatic Ductal Adenocarcinoma Metastasis after Gemcitabine Treatment

Despite substantial advances in the treatment of solid cancers, resistance to therapy remains a major obstacle to prolonged progression-free survival. Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers, with a high level of liver metastasis. Primary PDAC is highly hypoxic,...

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Detalles Bibliográficos
Autores principales: Roy-Luzarraga, Marina, Reynolds, Louise E., de Luxán-Delgado, Beatriz, Maiques, Oscar, Wisniewski, Laura, Newport, Emma, Rajeeve, Vinothini, Drake, Rebecca J.G., Gómez-Escudero, Jesús, Richards, Frances M., Weller, Céline, Dormann, Christof, Meng, Ya-Ming, Vermeulen, Peter B., Saur, Dieter, Sanz-Moreno, Victoria, Wong, Ping-Pui, Géraud, Cyrill, Cutillas, Pedro R., Hodivala-Dilke, Kairbaan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Molecular Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381116/
https://www.ncbi.nlm.nih.gov/pubmed/35350066
http://dx.doi.org/10.1158/0008-5472.CAN-20-3807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381116/
https://www.ncbi.nlm.nih.gov/pubmed/35350066
http://dx.doi.org/10.1158/0008-5472.CAN-20-3807

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