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Identification of Cytosolic DNA Sensor cGAS-STING as Immune-Related Risk Factor in Renal Carcinoma following Pan-Cancer Analysis

BACKGROUND: The cytosolic DNA sensor cyclic GMP-AMP synthase (cGAS) plays critical functions in innate immune responses via the production of the second messenger cyclic guanosine monophosphate-adenosine monophosphate (cGAMP), which stimulates the adaptor stimulator of interferon genes (STING). Howe...

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Detalles Bibliográficos
Autores principales: Wu, Zheng, Lin, Ying, Liu, Li-Min, Hou, Yan-Li, Qin, Wei-Ting, Zhang, Lei, Jiang, Shu-Heng, Yang, Qin, Bai, Yong-Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381291/
https://www.ncbi.nlm.nih.gov/pubmed/35983076
http://dx.doi.org/10.1155/2022/7978042