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In-vivo pharmacokinetic studies of Dolutegravir loaded spray dried Chitosan nanoparticles as milk admixture for paediatrics infected with HIV

Dolutegravir (DTG) is an antiretroviral drug approved in the year 2013, and being categorized as a BCS-II molecule, it possesses solubility issues. In order to enhance the solubility and improve its bioavailability, DTG-loaded Chitosan nanoparticles (NPs) were synthesized utilizing spray drying tech...

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Detalles Bibliográficos
Autores principales:	K, Priya Dharshini, D, Ramya Devi, S, Banudevi, B. Narayanan, Vedha Hari
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381509/ https://www.ncbi.nlm.nih.gov/pubmed/35974065 http://dx.doi.org/10.1038/s41598-022-18009-x

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