The addition of FAIMS increases targeted proteomics sensitivity from FFPE tumor biopsies

Mass spectrometry-based targeted proteomics allows objective protein quantitation of clinical biomarkers from a single section of formalin-fixed, paraffin-embedded (FFPE) tumor tissue biopsies. We combined high-field asymmetric waveform ion mobility spectrometry (FAIMS) and parallel reaction monitor...

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Detalles Bibliográficos
Autores principales: Sweet, Steve, Chain, David, Yu, Wen, Martin, Philip, Rebelatto, Marlon, Chambers, Andrew, Cecchi, Fabiola, Kim, Yeoun Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381555/
https://www.ncbi.nlm.nih.gov/pubmed/35974054
http://dx.doi.org/10.1038/s41598-022-16358-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381555/
https://www.ncbi.nlm.nih.gov/pubmed/35974054
http://dx.doi.org/10.1038/s41598-022-16358-1

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