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Regulatory T cells induce a suppressive immune milieu and promote lymph node metastasis in intrahepatic cholangiocarcinoma

BACKGROUND: Emerging evidence indicates that immunogenicity plays an important role in intrahepatic cholangiocarcinoma (ICC). Herein, we systematically evaluated the clinical relevance of immunogenicity in ICC. METHODS: Highly immunogenic ICCs identified in the public dataset and the Cancer Immunome...

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Detalles Bibliográficos
Autores principales: Konishi, Daisuke, Umeda, Yuzo, Yoshida, Kazuhiro, Shigeyasu, Kunitoshi, Yano, Shuya, Toji, Tomohiro, Takeda, Sho, Yoshida, Ryuichi, Yasui, Kazuya, Fuji, Tomokazu, Matsumoto, Kazuyuki, Kishimoto, Hiroyuki, Michiue, Hiroyuki, Teraishi, Fuminori, Kato, Hironari, Tazawa, Hiroshi, Yanai, Hiroyuki, Yagi, Takahito, Goel, Ajay, Fujiwara, Toshiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381563/
https://www.ncbi.nlm.nih.gov/pubmed/35597869
http://dx.doi.org/10.1038/s41416-022-01838-y