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RNA sequencing-based single sample predictors of molecular subtype and risk of recurrence for clinical assessment of early-stage breast cancer

Multigene assays for molecular subtypes and biomarkers can aid management of early invasive breast cancer. Using RNA-sequencing we aimed to develop single-sample predictor (SSP) models for clinical markers, subtypes, and risk of recurrence (ROR). A cohort of 7743 patients was divided into training a...

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Detalles Bibliográficos
Autores principales:	Staaf, Johan, Häkkinen, Jari, Hegardt, Cecilia, Saal, Lao H., Kimbung, Siker, Hedenfalk, Ingrid, Lien, Tonje, Sørlie, Therese, Naume, Bjørn, Russnes, Hege, Marcone, Rachel, Ayyanan, Ayyakkannu, Brisken, Cathrin, Malterling, Rebecka R., Asking, Bengt, Olofsson, Helena, Lindman, Henrik, Bendahl, Pär-Ola, Ehinger, Anna, Larsson, Christer, Loman, Niklas, Rydén, Lisa, Malmberg, Martin, Borg, Åke, Vallon-Christersson, Johan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381586/ https://www.ncbi.nlm.nih.gov/pubmed/35974007 http://dx.doi.org/10.1038/s41523-022-00465-3

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