MBD3 promotes hepatocellular carcinoma progression and metastasis through negative regulation of tumour suppressor TFPI2

BACKGROUND: The mechanism of recurrence and metastasis of hepatocellular carcinoma (HCC) is complex and challenging. Methyl-CpG binding domain protein 3 (MBD3) is a key epigenetic regulator involved in the progression and metastasis of several cancers, but its role in HCC remains unknown. METHODS: M...

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Detalles Bibliográficos
Autores principales: Yan, Weiwei, Han, Qiuying, Gong, Lin, Zhan, Xiaoyan, Li, Wanjin, Guo, Zenglin, Zhao, Jiangman, Li, Tingting, Bai, Zhaofang, Wu, Jin, Huang, Yan, Lv, Luye, Zhao, Haixin, Cai, Hong, Huang, Shaoyi, Diao, Xinwei, Chen, Yuan, Gong, Weili, Xia, Qing, Man, Jianghong, Chen, Liang, Dai, Guanghai, Zhou, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381593/
https://www.ncbi.nlm.nih.gov/pubmed/35501390
http://dx.doi.org/10.1038/s41416-022-01831-5

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