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Personalised selection of experimental treatment in patients with advanced solid cancer is feasible using whole-genome sequencing
BACKGROUND: Biomarker-guided therapy in an experimental setting has been suggested to improve patient outcomes. However, trial-specific pre-screening tests are time and tissue consuming and complicate the personalised treatment of patients eligible for early-phase clinical trials. In this study the...
Autores principales: | Pruis, Melinda A., Groenendijk, Floris H., Badloe, K. Sangeeta, van Puffelen, Andrea, Robbrecht, Debbie, Dinjens, Winand N. M., Sleijfer, Stefan, Dingemans, Anne-Marie C., von der Thüsen, Jan H., Roepman, Paul, Lolkema, Martijn P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381598/ https://www.ncbi.nlm.nih.gov/pubmed/35606463 http://dx.doi.org/10.1038/s41416-022-01841-3 |
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