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DNA damage-induced paraspeckle formation enhances DNA repair and tumor radioresistance by recruiting ribosomal protein P0

Paraspeckles are mammal-specific membraneless nuclear bodies that participate in various biological processes. NONO, a central paraspeckle component, has been shown to play pivotal roles in DNA double-strand breaks (DSB) repair, whereas its underlying mechanism needs to be further disclosed. Here, u...

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Detalles Bibliográficos
Autores principales: Wang, Yun-Long, Zhao, Wan-Wen, Bai, Shao-Mei, Ma, Yan, Yin, Xin-Ke, Feng, Li-Li, Zeng, Guang-Dong, Wang, Fang, Feng, Wei-Xing, Zheng, Jian, Wang, Ying-Nai, Zeng, Bing, Liu, Quentin, Hung, Mien-Chie, Wan, Xiang-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381602/
https://www.ncbi.nlm.nih.gov/pubmed/35974014
http://dx.doi.org/10.1038/s41419-022-05092-1

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