Effects of Itraconazole and Diltiazem on the Pharmacokinetics and Pharmacodynamics of Milvexian, A Factor XIa Inhibitor

INTRODUCTION: Modulation of Factor XIa (FXIa) may provide a novel mechanism for systemic anticoagulation with the potential to improve the risk-benefit profile observed with existing anticoagulants through greater efficacy or a safer bleeding profile. This study assessed the effects of co-administra...

Descripción completa

Detalles Bibliográficos
Autores principales: Perera, Vidya, Wang, Zhaoqing, Lubin, Susan, Christopher, Lisa J., Chen, Wei, Xu, Sophia, Seiffert, Dietmar, DeSouza, Mary, Murthy, Bindu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381674/
https://www.ncbi.nlm.nih.gov/pubmed/35641780
http://dx.doi.org/10.1007/s40119-022-00266-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381674/
https://www.ncbi.nlm.nih.gov/pubmed/35641780
http://dx.doi.org/10.1007/s40119-022-00266-6

Ejemplares similares