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Transient reduction in dendritic spine density in brain-specific profilin1 mutant mice is associated with behavioral deficits
Actin filaments form the backbone of dendritic spines, the postsynaptic compartment of most excitatory synapses in the brain. Spine density changes affect brain function, and postsynaptic actin defects have been implicated in various neuropathies. It is mandatory to identify the actin regulators tha...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381693/ https://www.ncbi.nlm.nih.gov/pubmed/35992199 http://dx.doi.org/10.3389/fnmol.2022.952782 |