STAT1 is regulated by TRIM24 and promotes immunosuppression in head and neck squamous carcinoma cells, but enhances T cell antitumour immunity in the tumour microenvironment

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is a significant problem and is frequently resistant to current treatments. STAT1 is important in anti-tumour immune responses against HNSCC. However, the role of STAT1 expression by tumour cells and its regulation during HNSCC is unclear. ME...

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Detalles Bibliográficos
Autores principales: Anderson, Kelvin, Ryan, Nathan, Nedungadi, Divya, Lamenza, Felipe, Swingler, Michael, Siddiqui, Arham, Satoskar, Abhay, Upadhaya, Puja, Pietrzak, Maciej, Oghumu, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381763/
https://www.ncbi.nlm.nih.gov/pubmed/35595823
http://dx.doi.org/10.1038/s41416-022-01853-z

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