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Synergistic effects of nab-PTX and anti-PD-1 antibody combination against lung cancer by regulating the Pi3K/AKT pathway through the Serpinc1 gene

Lung cancer is a type of cancer with higher morbidity and mortality. In spite of the impressive response rates of nab-paclitaxel (nab-PTX) or programmed cell death-1 (PD-1) and its ligand inhibitors, the effective treatment remains limited. Currently, alternative strategies aim at drug combination o...

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Detalles Bibliográficos
Autores principales: Zhang, Jun, Tang, Zhijia, Guo, Xi, Wang, Yunxia, Zhou, Yuhong, Cai, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381811/
https://www.ncbi.nlm.nih.gov/pubmed/35992834
http://dx.doi.org/10.3389/fonc.2022.933646