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Homologous recombination repair gene mutations as a predictive biomarker for immunotherapy in patients with advanced melanoma

BACKGROUND: Nowadays, immunotherapy targeting immune checkpoint receptors is one of the cornerstones of systemic treatment in melanoma. Homologous recombination repair (HRR) is one of the DNA damage response (DDR) pathways, which has been proved to correlate with the efficacy of platinum-based chemo...

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Detalles Bibliográficos
Autores principales:	You, Zhixuan, Lv, Meng, He, Xuanyu, Pan, Yingqin, Ge, Junfeng, Hu, Xue, Zheng, Yating, Huang, Mengli, Zhou, Chengzhi, You, Changxuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381822/ https://www.ncbi.nlm.nih.gov/pubmed/35990677 http://dx.doi.org/10.3389/fimmu.2022.871756

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