p38α‐MAPK‐deficient myeloid cells ameliorate symptoms and pathology of APP‐transgenic Alzheimer's disease mice

Alzheimer's disease (AD), the most common cause of dementia in the elderly, is pathologically characterized by extracellular deposition of amyloid‐β peptides (Aβ) and microglia‐dominated inflammatory activation in the brain. p38α‐MAPK is activated in both neurons and microglia. How p38α‐MAPK in...

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Detalles Bibliográficos
Autores principales: Luo, Qinghua, Schnöder, Laura, Hao, Wenlin, Litzenburger, Kathrin, Decker, Yann, Tomic, Inge, Menger, Michael D., Liu, Yang, Fassbender, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381888/
https://www.ncbi.nlm.nih.gov/pubmed/35909315
http://dx.doi.org/10.1111/acel.13679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381888/
https://www.ncbi.nlm.nih.gov/pubmed/35909315
http://dx.doi.org/10.1111/acel.13679

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