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p38α‐MAPK‐deficient myeloid cells ameliorate symptoms and pathology of APP‐transgenic Alzheimer's disease mice
Alzheimer's disease (AD), the most common cause of dementia in the elderly, is pathologically characterized by extracellular deposition of amyloid‐β peptides (Aβ) and microglia‐dominated inflammatory activation in the brain. p38α‐MAPK is activated in both neurons and microglia. How p38α‐MAPK in...
Autores principales: | Luo, Qinghua, Schnöder, Laura, Hao, Wenlin, Litzenburger, Kathrin, Decker, Yann, Tomic, Inge, Menger, Michael D., Liu, Yang, Fassbender, Klaus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381888/ https://www.ncbi.nlm.nih.gov/pubmed/35909315 http://dx.doi.org/10.1111/acel.13679 |
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