p300 arrests intervertebral disc degeneration by regulating the FOXO3/Sirt1/Wnt/β‐catenin axis

The transcription factor p300 is reportedly involved in age‐associated human diseases, including intervertebral disc degeneration (IDD). In this study, we investigate the potential role and pathophysiological mechanism of p300 in IDD. Clinical tissue samples were collected from patients with lumbar...

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Detalles Bibliográficos
Autores principales: Hao, Yingjie, Ren, Zhinan, Yu, Lei, Zhu, Guangduo, Zhang, Panke, Zhu, Jian, Cao, Shuyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381896/
https://www.ncbi.nlm.nih.gov/pubmed/35907249
http://dx.doi.org/10.1111/acel.13677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381896/
https://www.ncbi.nlm.nih.gov/pubmed/35907249
http://dx.doi.org/10.1111/acel.13677

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