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DAF‐2/insulin IGF‐1 receptor regulates motility during aging by integrating opposite signaling from muscle and neuronal tissues
During aging, preservation of locomotion is generally considered an indicator of sustained good health, in elderlies and in animal models. In Caenorhabditis elegans, mutants of the insulin‐IGF‐1 receptor DAF2/IIRc represent a paradigm of healthy aging, as their increased lifespan is accompanied by a...
Autores principales: | Roy, Charline, Molin, Laurent, Alcolei, Allan, Solyga, Mathilde, Bonneau, Benjamin, Vachon, Camille, Bessereau, Jean‐Louis, Solari, Florence |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381905/ https://www.ncbi.nlm.nih.gov/pubmed/35808897 http://dx.doi.org/10.1111/acel.13660 |
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