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The area under the effect curve as an efficacy determinant for anti‐infectives
Pharmacokinetic/pharmacodynamic (PK/PD) indices making use of area under the curve, maximum concentration, and the duration that in vivo drug concentration is maintained above a critical level are commonly applied to clinical dose prediction from animal efficacy experiments in the infectious disease...
Autores principales: | Chen, Chao, Lavezzi, Silvia Maria, Iavarone, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381909/ https://www.ncbi.nlm.nih.gov/pubmed/35638366 http://dx.doi.org/10.1002/psp4.12811 |
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