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Microneedling combined with compound betamethasone in treatment of severe alopecia areata: A case report

Alopecia areata (AA) is a common inflammatory, non-cicatricial hair loss. At present, it is considered that its pathogenesis is an autoimmune disease specific to hair follicle organs mediated by T cells under the combined action of genetic and environmental factors. Treatment is challenging for chil...

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Autores principales: Pei, Danning, Chen, Lirong, Yao, Yue, Zeng, Linxi, Zhang, Guoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381928/
https://www.ncbi.nlm.nih.gov/pubmed/35990624
http://dx.doi.org/10.3389/fimmu.2022.939077
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author Pei, Danning
Chen, Lirong
Yao, Yue
Zeng, Linxi
Zhang, Guoqiang
author_facet Pei, Danning
Chen, Lirong
Yao, Yue
Zeng, Linxi
Zhang, Guoqiang
author_sort Pei, Danning
collection PubMed
description Alopecia areata (AA) is a common inflammatory, non-cicatricial hair loss. At present, it is considered that its pathogenesis is an autoimmune disease specific to hair follicle organs mediated by T cells under the combined action of genetic and environmental factors. Treatment is challenging for children with severe AA who are resistant or intolerant to conventional treatment.Here, we treated a 3-year-old child with severe AA with microneedling combined with compound betamethasone. After 6 months of treatment, the patient’s condition was significantly improved, and most of the primary hair loss areas had hair regeneration.
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spelling pubmed-93819282022-08-18 Microneedling combined with compound betamethasone in treatment of severe alopecia areata: A case report Pei, Danning Chen, Lirong Yao, Yue Zeng, Linxi Zhang, Guoqiang Front Immunol Immunology Alopecia areata (AA) is a common inflammatory, non-cicatricial hair loss. At present, it is considered that its pathogenesis is an autoimmune disease specific to hair follicle organs mediated by T cells under the combined action of genetic and environmental factors. Treatment is challenging for children with severe AA who are resistant or intolerant to conventional treatment.Here, we treated a 3-year-old child with severe AA with microneedling combined with compound betamethasone. After 6 months of treatment, the patient’s condition was significantly improved, and most of the primary hair loss areas had hair regeneration. Frontiers Media S.A. 2022-08-03 /pmc/articles/PMC9381928/ /pubmed/35990624 http://dx.doi.org/10.3389/fimmu.2022.939077 Text en Copyright © 2022 Pei, Chen, Yao, Zeng and Zhang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Pei, Danning
Chen, Lirong
Yao, Yue
Zeng, Linxi
Zhang, Guoqiang
Microneedling combined with compound betamethasone in treatment of severe alopecia areata: A case report
title Microneedling combined with compound betamethasone in treatment of severe alopecia areata: A case report
title_full Microneedling combined with compound betamethasone in treatment of severe alopecia areata: A case report
title_fullStr Microneedling combined with compound betamethasone in treatment of severe alopecia areata: A case report
title_full_unstemmed Microneedling combined with compound betamethasone in treatment of severe alopecia areata: A case report
title_short Microneedling combined with compound betamethasone in treatment of severe alopecia areata: A case report
title_sort microneedling combined with compound betamethasone in treatment of severe alopecia areata: a case report
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381928/
https://www.ncbi.nlm.nih.gov/pubmed/35990624
http://dx.doi.org/10.3389/fimmu.2022.939077
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