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Punicalagin as an allosteric NSP13 helicase inhibitor potently suppresses SARS-CoV-2 replication in vitro

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) helicase NSP13 plays a conserved role in the replication of coronaviruses and has been identified as an ideal target for the development of antiviral drugs against SARS-CoV-2. Here, we identify a novel NSP13 helicase inhibitor punicala...

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Detalles Bibliográficos
Autores principales:	Lu, Lian, Peng, Yun, Yao, Huiqiao, Wang, Yanqun, Li, Jinyu, Yang, Yang, Lin, Zhonghui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381947/ https://www.ncbi.nlm.nih.gov/pubmed/35985407 http://dx.doi.org/10.1016/j.antiviral.2022.105389

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