Sex-specific differences in immunogenomic features of response to immune checkpoint blockade

INTRODUCTION: The magnitude of response to immune checkpoint inhibitor (ICI) therapy may be sex-dependent, as females have lower response rates and decreased survival after ICI monotherapy. The mechanisms underlying this sex dimorphism in ICI response are unknown, and may be related to sex-driven di...

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Detalles Bibliográficos
Autores principales: Scott, Susan C., Shao, Xiaoshan M., Niknafs, Noushin, Balan, Archana, Pereira, Gavin, Marrone, Kristen A., Lam, Vincent K., Murray, Joseph C., Feliciano, Josephine L., Levy, Benjamin P., Ettinger, David S., Hann, Christine L., Brahmer, Julie R., Forde, Patrick M., Karchin, Rachel, Naidoo, Jarushka, Anagnostou, Valsamo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382103/
https://www.ncbi.nlm.nih.gov/pubmed/35992816
http://dx.doi.org/10.3389/fonc.2022.945798

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