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Activation of TRPC6 by AngⅡ Induces Podocyte Injury and Participates in Proteinuria of Nephrotic Syndrome

Background: Nephrotic syndrome (NS) is a common glomerular disease, and podocyte injury is the character of primary NS, usually caused by minimal change disease and membranous nephropathy. Podocytopathy is primarily associated with glomerular proteinuria. Losartan, an angiotensin receptor blocker (A...

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Detalles Bibliográficos
Autores principales: Feng, Ye, Li, Manman, Wang, Yunlai, Yang, Mo, Shi, Gaoxiang, Yin, Dengke, Xuan, Zihua, Xu, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382118/
https://www.ncbi.nlm.nih.gov/pubmed/35991898
http://dx.doi.org/10.3389/fphar.2022.915153