Combined treatment with epigenetic agents enhances anti-tumor activity of MAGE-D4 peptide-specific T cells by upregulating the MAGE-D4 expression in glioma

OBJECTIVE: The study evaluated the efficacy of combined epigenetic drugs of decitabine (DAC), valproic acid (VPA), and trichostatin A (TSA) on immunotherapy against glioma. METHODS: The expression and prognosis of MAGE-D4 in glioma were analyzed online, and the expression of MAGE-D4 and HLA-A2 in gl...

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Detalles Bibliográficos
Autores principales: Bi, Shui-Qing, Zhang, Qing-Mei, Zeng, Xia, Liu, Chang, Nong, Wei-Xia, Xie, Huan, Li, Feng, Lin, Li-Na, Luo, Bin, Ge, Ying-Ying, Xie, Xiao-Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382192/
https://www.ncbi.nlm.nih.gov/pubmed/35992806
http://dx.doi.org/10.3389/fonc.2022.873639

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