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Revisiting the origin of interleukin 1 in anamniotes and sub-functionalization of interleukin 1 in amniotes

The cytokine interleukin 1 (IL-1) is an evolutionary innovation of vertebrates. Fish and amphibian have one IL1 gene, while mammals have two copies of IL1, IL1A and IL1B, with distinct expression patterns and differences in their proteolytic activation. Our current understanding of the evolutionary...

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Detalles Bibliográficos
Autores principales:	Hasel de Carvalho, Eva, Bartok, Eva, Stölting, Helen, Bajoghli, Baubak, Leptin, Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382457/ https://www.ncbi.nlm.nih.gov/pubmed/35975650 http://dx.doi.org/10.1098/rsob.220049

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