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Diagnosis and treatment of bbstetrics disseminated intravascular coagulation in resource limited settings

BACKGROUND: Disseminated intravascular coagulation (DIC) is one of the commonest causes of abnormal bleeding during pregnancy and puerperium. Its successful management is a challenging feat in resource limited settings (RLS). AIM: To determine Obstetricians' approach in diagnosing and treating...

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Detalles Bibliográficos
Autores principales: Okoye, Helen C, Nwagha, Theresa U, Ugwu, Angela O, Menuba, Ifeanyi E, Duru, Augustine N, Ugwu, Emmanuel O, Ezebialu, Feanyichukwu U, Eze, Stephen C, Ugwu, Aloysuis O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Makerere Medical School 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382527/
https://www.ncbi.nlm.nih.gov/pubmed/36032500
http://dx.doi.org/10.4314/ahs.v22i1.24
Descripción
Sumario:BACKGROUND: Disseminated intravascular coagulation (DIC) is one of the commonest causes of abnormal bleeding during pregnancy and puerperium. Its successful management is a challenging feat in resource limited settings (RLS). AIM: To determine Obstetricians' approach in diagnosing and treating obstetrics DIC in a RLS METHOD: A semi-structured pre-tested 4-sectioned questionnaire was used to collect demographic data of Nigerian obstetricians and data on their practice in the diagnosis and treatment of obstetrics DIC. RESULTS: A total of 171 obstetricians responded. Preeclampsia was the most frequent cause identified (70.2%) followed by postpartum haemorrahge (58.3%). Platelet count determination was the test mostly used (95.9%) to make a diagnosis of DIC whereas, antithrombin assay was the least (20.6%) requested investigation. While about two-third would monitor the evolution of DIC, a little less than half of the obstetricians would not repeat laboratory testing more than every 2 days, reason mainly (61.8%) due to patient's financial constraint. Almost three-quarter of them preferred fresh whole blood as the first line of treatment of DIC. CONCLUSION: DIC remains a challenge in the obstetrics practice in RLS especially in investigations, monitoring and index of suspicion for non-overt DIC.