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Diagnosis and treatment of bbstetrics disseminated intravascular coagulation in resource limited settings

BACKGROUND: Disseminated intravascular coagulation (DIC) is one of the commonest causes of abnormal bleeding during pregnancy and puerperium. Its successful management is a challenging feat in resource limited settings (RLS). AIM: To determine Obstetricians' approach in diagnosing and treating...

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Autores principales: Okoye, Helen C, Nwagha, Theresa U, Ugwu, Angela O, Menuba, Ifeanyi E, Duru, Augustine N, Ugwu, Emmanuel O, Ezebialu, Feanyichukwu U, Eze, Stephen C, Ugwu, Aloysuis O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Makerere Medical School 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382527/
https://www.ncbi.nlm.nih.gov/pubmed/36032500
http://dx.doi.org/10.4314/ahs.v22i1.24
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author Okoye, Helen C
Nwagha, Theresa U
Ugwu, Angela O
Menuba, Ifeanyi E
Duru, Augustine N
Ugwu, Emmanuel O
Ezebialu, Feanyichukwu U
Eze, Stephen C
Ugwu, Aloysuis O
author_facet Okoye, Helen C
Nwagha, Theresa U
Ugwu, Angela O
Menuba, Ifeanyi E
Duru, Augustine N
Ugwu, Emmanuel O
Ezebialu, Feanyichukwu U
Eze, Stephen C
Ugwu, Aloysuis O
author_sort Okoye, Helen C
collection PubMed
description BACKGROUND: Disseminated intravascular coagulation (DIC) is one of the commonest causes of abnormal bleeding during pregnancy and puerperium. Its successful management is a challenging feat in resource limited settings (RLS). AIM: To determine Obstetricians' approach in diagnosing and treating obstetrics DIC in a RLS METHOD: A semi-structured pre-tested 4-sectioned questionnaire was used to collect demographic data of Nigerian obstetricians and data on their practice in the diagnosis and treatment of obstetrics DIC. RESULTS: A total of 171 obstetricians responded. Preeclampsia was the most frequent cause identified (70.2%) followed by postpartum haemorrahge (58.3%). Platelet count determination was the test mostly used (95.9%) to make a diagnosis of DIC whereas, antithrombin assay was the least (20.6%) requested investigation. While about two-third would monitor the evolution of DIC, a little less than half of the obstetricians would not repeat laboratory testing more than every 2 days, reason mainly (61.8%) due to patient's financial constraint. Almost three-quarter of them preferred fresh whole blood as the first line of treatment of DIC. CONCLUSION: DIC remains a challenge in the obstetrics practice in RLS especially in investigations, monitoring and index of suspicion for non-overt DIC.
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spelling pubmed-93825272022-08-25 Diagnosis and treatment of bbstetrics disseminated intravascular coagulation in resource limited settings Okoye, Helen C Nwagha, Theresa U Ugwu, Angela O Menuba, Ifeanyi E Duru, Augustine N Ugwu, Emmanuel O Ezebialu, Feanyichukwu U Eze, Stephen C Ugwu, Aloysuis O Afr Health Sci Articles BACKGROUND: Disseminated intravascular coagulation (DIC) is one of the commonest causes of abnormal bleeding during pregnancy and puerperium. Its successful management is a challenging feat in resource limited settings (RLS). AIM: To determine Obstetricians' approach in diagnosing and treating obstetrics DIC in a RLS METHOD: A semi-structured pre-tested 4-sectioned questionnaire was used to collect demographic data of Nigerian obstetricians and data on their practice in the diagnosis and treatment of obstetrics DIC. RESULTS: A total of 171 obstetricians responded. Preeclampsia was the most frequent cause identified (70.2%) followed by postpartum haemorrahge (58.3%). Platelet count determination was the test mostly used (95.9%) to make a diagnosis of DIC whereas, antithrombin assay was the least (20.6%) requested investigation. While about two-third would monitor the evolution of DIC, a little less than half of the obstetricians would not repeat laboratory testing more than every 2 days, reason mainly (61.8%) due to patient's financial constraint. Almost three-quarter of them preferred fresh whole blood as the first line of treatment of DIC. CONCLUSION: DIC remains a challenge in the obstetrics practice in RLS especially in investigations, monitoring and index of suspicion for non-overt DIC. Makerere Medical School 2022-03 /pmc/articles/PMC9382527/ /pubmed/36032500 http://dx.doi.org/10.4314/ahs.v22i1.24 Text en © 2022 Okoye HC et al. https://creativecommons.org/licenses/by/4.0/Licensee African Health Sciences. This is an Open Access article distributed under the terms of the Creative commons Attribution License (https://creativecommons.org/licenses/BY/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Okoye, Helen C
Nwagha, Theresa U
Ugwu, Angela O
Menuba, Ifeanyi E
Duru, Augustine N
Ugwu, Emmanuel O
Ezebialu, Feanyichukwu U
Eze, Stephen C
Ugwu, Aloysuis O
Diagnosis and treatment of bbstetrics disseminated intravascular coagulation in resource limited settings
title Diagnosis and treatment of bbstetrics disseminated intravascular coagulation in resource limited settings
title_full Diagnosis and treatment of bbstetrics disseminated intravascular coagulation in resource limited settings
title_fullStr Diagnosis and treatment of bbstetrics disseminated intravascular coagulation in resource limited settings
title_full_unstemmed Diagnosis and treatment of bbstetrics disseminated intravascular coagulation in resource limited settings
title_short Diagnosis and treatment of bbstetrics disseminated intravascular coagulation in resource limited settings
title_sort diagnosis and treatment of bbstetrics disseminated intravascular coagulation in resource limited settings
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382527/
https://www.ncbi.nlm.nih.gov/pubmed/36032500
http://dx.doi.org/10.4314/ahs.v22i1.24
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