Rapid and selective generation of H(2)S within mitochondria protects against cardiac ischemia-reperfusion injury

Mitochondria-targeted H(2)S donors are thought to protect against acute ischemia-reperfusion (IR) injury by releasing H(2)S that decreases oxidative damage. However, the rate of H(2)S release by current donors is too slow to be effective upon administration following reperfusion. To overcome this li...

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Detalles Bibliográficos
Autores principales: Miljkovic, Jan Lj., Burger, Nils, Gawel, Justyna M., Mulvey, John F., Norman, Abigail A.I., Nishimura, Takanori, Tsujihata, Yoshiyuki, Logan, Angela, Sauchanka, Olga, Caldwell, Stuart T., Morris, Jordan L., Prime, Tracy A., Warrington, Stefan, Prudent, Julien, Bates, Georgina R., Aksentijević, Dunja, Prag, Hiran A., James, Andrew M., Krieg, Thomas, Hartley, Richard C., Murphy, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382561/
https://www.ncbi.nlm.nih.gov/pubmed/35961099
http://dx.doi.org/10.1016/j.redox.2022.102429

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