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Assessment of the Intestinal Absorption of Higher Olefins by the Everted Gut Sac Model in Combination with In Silico New Approach Methodologies

[Image: see text] To reduce the number of animals and studies needed to fulfill the information requirements as required by Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) (EC no. 1907/2006), a read-across approach was used to support approximately 30 higher olefins. Thi...

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Detalles Bibliográficos
Autores principales:	Shi, Quan, Carrillo, Juan-Carlos, Penman, Michael G., Manton, Jason, Fioravanzo, Elena, Powrie, Robert H., Elcombe, Clifford R., Borsboom-Patel, Tilly, Tian, Yuan, Shen, Hua, Boogaard, Peter J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382673/ https://www.ncbi.nlm.nih.gov/pubmed/35830964 http://dx.doi.org/10.1021/acs.chemrestox.2c00089

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