Cargando…

HMGB1 in the mPFC governs comorbid anxiety in neuropathic pain

BACKGROUND: Whether neuroinflammation causes comorbid mood disorders in neuropathic pain remains elusive. Here we investigated the role of high mobility group box 1 protein (HMGB1), a proinflammatory cytokine, in the medial prefrontal cortex (mPFC) in anxiety comorbidity of neuropathic pain. METHODS...

Descripción completa

Detalles Bibliográficos
Autores principales: Du, Yu, Xu, Ceng-Lin, Yu, Jie, Liu, Keyue, Lin, Shi-Da, Hu, Ting-Ting, Qu, Feng-Hui, Guo, Fang, Lou, Guo-Dong, Nishibori, Masahiro, Hu, Wei-Wei, Chen, Zhong, Zhang, Shi-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382735/
https://www.ncbi.nlm.nih.gov/pubmed/35974316
http://dx.doi.org/10.1186/s10194-022-01475-z