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HMGB1 in the mPFC governs comorbid anxiety in neuropathic pain
BACKGROUND: Whether neuroinflammation causes comorbid mood disorders in neuropathic pain remains elusive. Here we investigated the role of high mobility group box 1 protein (HMGB1), a proinflammatory cytokine, in the medial prefrontal cortex (mPFC) in anxiety comorbidity of neuropathic pain. METHODS...
Autores principales: | Du, Yu, Xu, Ceng-Lin, Yu, Jie, Liu, Keyue, Lin, Shi-Da, Hu, Ting-Ting, Qu, Feng-Hui, Guo, Fang, Lou, Guo-Dong, Nishibori, Masahiro, Hu, Wei-Wei, Chen, Zhong, Zhang, Shi-Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Milan
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382735/ https://www.ncbi.nlm.nih.gov/pubmed/35974316 http://dx.doi.org/10.1186/s10194-022-01475-z |
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