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Determinants of work and social participation in patients with psoriatic arthritis in the Netherlands: an observational study

BACKGROUND: Psoriatic arthritis can cause pain, disability, and permanent joint damage. This can lead to impairments in work and social participation. Little is known about the extent of these impairments in routine practice. With this study, we aim to examine the extent of work and activity impairm...

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Autores principales: van Hal, Tamara W., Mulder, Michelle L. M., Wenink, Mark H., Vriezekolk, Johanna E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382787/
https://www.ncbi.nlm.nih.gov/pubmed/35974423
http://dx.doi.org/10.1186/s41927-022-00279-7
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author van Hal, Tamara W.
Mulder, Michelle L. M.
Wenink, Mark H.
Vriezekolk, Johanna E.
author_facet van Hal, Tamara W.
Mulder, Michelle L. M.
Wenink, Mark H.
Vriezekolk, Johanna E.
author_sort van Hal, Tamara W.
collection PubMed
description BACKGROUND: Psoriatic arthritis can cause pain, disability, and permanent joint damage. This can lead to impairments in work and social participation. Little is known about the extent of these impairments in routine practice. With this study, we aim to examine the extent of work and activity impairment in (subgroups of) Dutch patients with psoriatic arthritis (PsA), and to examine determinants associated with this impairment. METHODS: This is an observational study using data collected from the electronic health records of PsA patients treated at the Sint Maartenskliniek, the Netherlands. Data about work and activity impairment were collected via the Work Productivity and Activity Impairment questionnaire. To compare our PsA-cohort with the Dutch general population, we used age- and sex-matched data derived from the Central Bureau of Statistics. Regression analyses were performed to examine determinants of work and activity impairment. RESULTS: In total, 246 patients were included, of which 126 (51.2%) were female. Mean age (S.D.) was 55.7 (13.2) years. Compared with the Dutch general population, work for pay (WFP) was significantly lower in PsA (52.9% versus 62.6%, P < 0.001). In PsA, younger age and better physical function were associated with WFP status (P < 0.05). Higher disease activity, worse physical function, and worse mental health-related quality of life were associated with both more work and activity impairment (P < 0.05). Furthermore, reaching low disease activity status (LDA) according to Psoriatic ArthritiS Disease Activity Score (PASDAS; ≤ 3.2) was associated with less work and activity impairment than reaching LDA according to DAS28-CRP (≤ 2.9) (P < 0.05). CONCLUSIONS: In PsA patients, worse physical function was associated with a lower likelihood of having WFP, and higher work and activity impairment. PASDAS LDA as a goal for treat to target, compared to DAS28-CRP, appears to favour the reduction of work and activity impairment. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s41927-022-00279-7.
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spelling pubmed-93827872022-08-18 Determinants of work and social participation in patients with psoriatic arthritis in the Netherlands: an observational study van Hal, Tamara W. Mulder, Michelle L. M. Wenink, Mark H. Vriezekolk, Johanna E. BMC Rheumatol Research BACKGROUND: Psoriatic arthritis can cause pain, disability, and permanent joint damage. This can lead to impairments in work and social participation. Little is known about the extent of these impairments in routine practice. With this study, we aim to examine the extent of work and activity impairment in (subgroups of) Dutch patients with psoriatic arthritis (PsA), and to examine determinants associated with this impairment. METHODS: This is an observational study using data collected from the electronic health records of PsA patients treated at the Sint Maartenskliniek, the Netherlands. Data about work and activity impairment were collected via the Work Productivity and Activity Impairment questionnaire. To compare our PsA-cohort with the Dutch general population, we used age- and sex-matched data derived from the Central Bureau of Statistics. Regression analyses were performed to examine determinants of work and activity impairment. RESULTS: In total, 246 patients were included, of which 126 (51.2%) were female. Mean age (S.D.) was 55.7 (13.2) years. Compared with the Dutch general population, work for pay (WFP) was significantly lower in PsA (52.9% versus 62.6%, P < 0.001). In PsA, younger age and better physical function were associated with WFP status (P < 0.05). Higher disease activity, worse physical function, and worse mental health-related quality of life were associated with both more work and activity impairment (P < 0.05). Furthermore, reaching low disease activity status (LDA) according to Psoriatic ArthritiS Disease Activity Score (PASDAS; ≤ 3.2) was associated with less work and activity impairment than reaching LDA according to DAS28-CRP (≤ 2.9) (P < 0.05). CONCLUSIONS: In PsA patients, worse physical function was associated with a lower likelihood of having WFP, and higher work and activity impairment. PASDAS LDA as a goal for treat to target, compared to DAS28-CRP, appears to favour the reduction of work and activity impairment. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s41927-022-00279-7. BioMed Central 2022-08-17 /pmc/articles/PMC9382787/ /pubmed/35974423 http://dx.doi.org/10.1186/s41927-022-00279-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
van Hal, Tamara W.
Mulder, Michelle L. M.
Wenink, Mark H.
Vriezekolk, Johanna E.
Determinants of work and social participation in patients with psoriatic arthritis in the Netherlands: an observational study
title Determinants of work and social participation in patients with psoriatic arthritis in the Netherlands: an observational study
title_full Determinants of work and social participation in patients with psoriatic arthritis in the Netherlands: an observational study
title_fullStr Determinants of work and social participation in patients with psoriatic arthritis in the Netherlands: an observational study
title_full_unstemmed Determinants of work and social participation in patients with psoriatic arthritis in the Netherlands: an observational study
title_short Determinants of work and social participation in patients with psoriatic arthritis in the Netherlands: an observational study
title_sort determinants of work and social participation in patients with psoriatic arthritis in the netherlands: an observational study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382787/
https://www.ncbi.nlm.nih.gov/pubmed/35974423
http://dx.doi.org/10.1186/s41927-022-00279-7
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