Translation of the 27-gene immuno-oncology test (IO score) to predict outcomes in immune checkpoint inhibitor treated metastatic urothelial cancer patients

BACKGROUND: The IO Score is a 27-gene immuno-oncology (IO) classifier that has previously predicted benefit to immune checkpoint inhibitor (ICI) therapy in triple negative breast cancer (TNBC) and non-small cell lung cancer (NSCLC). It generates both a continuous score and a binary result using a de...

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Detalles Bibliográficos
Autores principales: Seitz, Robert S., Hurwitz, Michael E., Nielsen, Tyler J., Bailey, Daniel B., Varga, Matthew G., Ring, Brian Z., Metts, Carrie F., Schweitzer, Brock L., McGregor, Kimberly, Ross, Douglas T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382843/
https://www.ncbi.nlm.nih.gov/pubmed/35974414
http://dx.doi.org/10.1186/s12967-022-03563-9

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