Cargando…

Gene expression and methylation profiles show the involvement of POMC in primary hyperparathyroidsm

Primary hyperparathyroidism (PHPT) is mainly caused by parathyroid adenoma, which produces excess parathyroid hormones. Its pathogenic mechanisms have not yet been fully understood. To investigate the mechanism in the pathogenesis of PHPT, the transcriptome and genome-wide DNA methylation profiles o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Wen-Xuan, Wang, Shu, Wu, Ting-Chao, Cheng, Ling-Chao, Du, Yao, Wu, Wei, Lin, Chen, Li, Xin-Ying, Hu, Zhong-Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382844/ https://www.ncbi.nlm.nih.gov/pubmed/35974370 http://dx.doi.org/10.1186/s12967-022-03568-4

Ejemplares similares

DNA methylation and expression of proopiomelanocortin (POMC) gene in the hypothalamus of three‐week‐old chickens show sex‐specific differences
por: Rancourt, Rebecca C., et al.
Publicado: (2018)

PERK in POMC neurons connects celastrol with metabolism
por: He, Zhenyan, et al.
Publicado: (2021)

Proopiomelanocortin (POMC) and psychodermatology
por: Millington, George W. M., et al.
Publicado: (2023)

Obesity, POMC, and POMC-processing Enzymes: Surprising Results From Animal Models
por: Lindberg, Iris, et al.
Publicado: (2021)

TLR4 in POMC neurons regulates thermogenesis in a sex-dependent manner
por: Li, Yongxiang, et al.
Publicado: (2023)

Amylin receptor insensitivity impairs hypothalamic POMC neuron differentiation in the male offspring of maternal high-fat diet-fed mice
por: Li, Cheng, et al.
Publicado: (2020)

Involvement of POMC neurons in LEAP2 regulation of food intake and body weight
por: Chu, Guangpin, et al.
Publicado: (2022)

Selective Restoration of Pomc Expression in Glutamatergic POMC Neurons: Evidence for a Dynamic Hypothalamic Neurotransmitter Network
por: Jones, Graham L., et al.
Publicado: (2019)

UCP2-dependent redox sensing in POMC neurons regulates feeding
por: Yoon, Nal Ae, et al.
Publicado: (2022)

Autophagic cell death participates in POMC-induced melanoma suppression
por: Wu, Jian-Ching, et al.
Publicado: (2018)

Arcuate hypothalamic AgRP and putative POMC neurons show opposite changes in spiking across multiple timescales
por: Mandelblat-Cerf, Yael, et al.
Publicado: (2015)

Adiponectin potentiates the acute effects of leptin in arcuate Pomc neurons
por: Sun, Jia, et al.
Publicado: (2016)

The role of proopiomelanocortin (POMC) neurones in feeding behaviour
por: Millington, George WM
Publicado: (2007)

The Involvement of Nek2 and Notch in the Proliferation of Rat Adrenal Cortex Triggered by POMC-Derived Peptides
por: de Mendonca, Pedro Omori Ribeiro, et al.
Publicado: (2014)

OR16-03 Metabolic Effects Of Hypothalamic Pomc Neurons Generated Postnatally From Tanycytes On A Pomc Null Genetic Background
por: Gahlot, Surbhi, et al.
Publicado: (2020)

Controlling hypothalamic DNA methylation at the Pomc promoter does not regulate weight gain during the development of obesity
por: McFadden, Taylor, et al.
Publicado: (2023)

Insulin regulates POMC neuronal plasticity to control glucose metabolism
por: Dodd, Garron T, et al.
Publicado: (2018)

TAp63 contributes to sexual dimorphism in POMC neuron functions and energy homeostasis
por: Wang, Chunmei, et al.
Publicado: (2018)

The stimulation of mitogenic signaling pathways by N-POMC peptides
por: Pepper, David J., et al.
Publicado: (2009)

Lactate activates hypothalamic POMC neurons by intercellular signaling
por: Órdenes, P., et al.
Publicado: (2021)

Association between the DNA methylations of POMC, MC4R, and HNF4A and metabolic profiles in the blood of children aged 7–9 years
por: Kwon, Eun Jin, et al.
Publicado: (2018)

TNFα drives mitochondrial stress in POMC neurons in obesity
por: Yi, Chun-Xia, et al.
Publicado: (2017)

POMC gene expression, polymorphism, and the association with reproduction traits in chickens
por: Liu, K., et al.
Publicado: (2020)

Role of POMC and AgRP neuronal activities on glycaemia in mice
por: Üner, Aykut Göktürk, et al.
Publicado: (2019)

Hypothalamic POMC deficiency increases circulating adiponectin despite obesity
por: Yu, Hui, et al.
Publicado: (2020)

Loss of POMC-mediated antinociception contributes to painful diabetic neuropathy
por: Deshpande, Divija, et al.
Publicado: (2021)

Duzhong Fang Attenuates the POMC-Derived Neuroinflammation in Parkinsonian Mice
por: Li, Lili, et al.
Publicado: (2021)

Whole-brain mapping of the direct inputs and axonal projections of POMC and AgRP neurons
por: Wang, Daqing, et al.
Publicado: (2015)

Epigenetic Alterations of the Promoter Region of the POMC Gene in Adolescent Depressive Disorder Patients with Nonsuicidal Self-injury Behaviors
por: Zheng, Doudou, et al.
Publicado: (2020)

DNA Methylation of POMC and NR3C1-1F and Its Implication in Major Depressive Disorder and Electroconvulsive Therapy
por: Maier, Hannah B., et al.
Publicado: (2023)

Long-Term Effects of Maternal Low-Protein Diet and Post-weaning High-Fat Feeding on Glucose Metabolism and Hypothalamic POMC Promoter Methylation in Offspring Mice
por: Zheng, Jia, et al.
Publicado: (2021)

Gene Expression and the Control of Food Intake by Hypothalamic POMC/CART Neurons
por: Hill, Jennifer W.
Publicado: (2010)

Defective regulation of POMC precedes hypothalamic inflammation in diet-induced obesity
por: Souza, Gabriela F. P., et al.
Publicado: (2016)

The Canine POMC Gene, Obesity in Labrador Retrievers and Susceptibility to Diabetes Mellitus
por: Davison, L.J., et al.
Publicado: (2017)

Energy imbalance alters Ca(2+) handling and excitability of POMC neurons
por: Paeger, Lars, et al.
Publicado: (2017)

Activation of the ARC(POMC)→MeA Projection Reduces Food Intake
por: Kwon, Eunjin, et al.
Publicado: (2020)

Two Distinctive POMC Promoters Modify Gene Expression in Cushing Disease
por: Araki, Takako, et al.
Publicado: (2021)

Hypothalamic CREB Regulates the Expression of Pomc-Processing Enzyme Pcsk2
por: Zanesco, Ariane Maria, et al.
Publicado: (2022)

Obesity and Hyperphagia With Increased Defective ACTH: A Novel POMC Variant
por: van der Valk, Eline S, et al.
Publicado: (2022)

Upregulation of hypothalamic POMC neurons after biliary diversion in GK rats
por: Zhou, Shengnan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_c4gqp67la9mej2occdfc5d2sa9