Postnatal eye size in mice is controlled by SREBP2-mediated transcriptional repression of Lrp2 and Bmp2

Eye size is a key parameter of visual function, but the precise mechanisms of eye size control remain poorly understood. Here, we discovered that the lipogenic transcription factor sterol regulatory element-binding protein 2 (SREBP2) has an unanticipated function in the retinal pigment epithelium (R...

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Detalles Bibliográficos
Autores principales: Mai, Shuyi, Zhu, Xiaoxuan, Wan, Esther Yi Ching, Wu, Shengyu, Yonathan, Jesslyn Nagalin, Wang, Jun, Li, Ying, Ma, Jessica Yuen Wuen, Zuo, Bing, Tse, Dennis Yan-yin, Lo, Pui-Chi, Wang, Xin, Chan, Kui Ming, Wu, David M., Xiong, Wenjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382895/
https://www.ncbi.nlm.nih.gov/pubmed/35833708
http://dx.doi.org/10.1242/dev.200633

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