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Enhanced development of functional human NK cells in NOD‐ scid‐IL2rg(null) mice expressing human IL15

Human innate immunity plays a critical role in tumor surveillance and in immunoregulation within the tumor microenvironment. Natural killer (NK) cells are innate lymphoid cells that have opposing roles in the tumor microenvironment, including NK cell subsets that mediate tumor cell cytotoxicity and...

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Detalles Bibliográficos
Autores principales: Aryee, Ken‐Edwin, Burzenski, Lisa M., Yao, Li‐Chin, Keck, James G., Greiner, Dale L., Shultz, Leonard D., Brehm, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9383543/
https://www.ncbi.nlm.nih.gov/pubmed/35959876
http://dx.doi.org/10.1096/fj.202200045R