High Asymptomatic Carriage With the Omicron Variant in South Africa

We report a 23% asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) Omicron carriage rate in participants being enrolled into a clinical trial in South Africa, 15-fold higher than in trials before Omicron. We also found lower CD4( + )T-cell counts in persons with human immunode...

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Detalles Bibliográficos
Autores principales: Garrett, Nigel, Tapley, Asa, Andriesen, Jessica, Seocharan, Ishen, Fisher, Leigh H, Bunts, Lisa, Espy, Nicole, Wallis, Carole L, Randhawa, April Kaur, Miner, Maurine D, Ketter, Nzeera, Yacovone, Margaret, Goga, Ameena, Huang, Yunda, Hural, John, Kotze, Philip, Bekker, Linda Gail, Gray, Glenda E, Corey, Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9383623/
https://www.ncbi.nlm.nih.gov/pubmed/35353885
http://dx.doi.org/10.1093/cid/ciac237
Descripción
Sumario:We report a 23% asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) Omicron carriage rate in participants being enrolled into a clinical trial in South Africa, 15-fold higher than in trials before Omicron. We also found lower CD4( + )T-cell counts in persons with human immunodeficiency virus (HIV) strongly correlated with increased odds of being SARS-CoV-2 polymerase chain reaction (PCR) positive.

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