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High Asymptomatic Carriage With the Omicron Variant in South Africa

We report a 23% asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) Omicron carriage rate in participants being enrolled into a clinical trial in South Africa, 15-fold higher than in trials before Omicron. We also found lower CD4( + )T-cell counts in persons with human immunode...

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Autores principales: Garrett, Nigel, Tapley, Asa, Andriesen, Jessica, Seocharan, Ishen, Fisher, Leigh H, Bunts, Lisa, Espy, Nicole, Wallis, Carole L, Randhawa, April Kaur, Miner, Maurine D, Ketter, Nzeera, Yacovone, Margaret, Goga, Ameena, Huang, Yunda, Hural, John, Kotze, Philip, Bekker, Linda Gail, Gray, Glenda E, Corey, Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9383623/
https://www.ncbi.nlm.nih.gov/pubmed/35353885
http://dx.doi.org/10.1093/cid/ciac237
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author Garrett, Nigel
Tapley, Asa
Andriesen, Jessica
Seocharan, Ishen
Fisher, Leigh H
Bunts, Lisa
Espy, Nicole
Wallis, Carole L
Randhawa, April Kaur
Miner, Maurine D
Ketter, Nzeera
Yacovone, Margaret
Goga, Ameena
Huang, Yunda
Hural, John
Kotze, Philip
Bekker, Linda Gail
Gray, Glenda E
Corey, Lawrence
author_facet Garrett, Nigel
Tapley, Asa
Andriesen, Jessica
Seocharan, Ishen
Fisher, Leigh H
Bunts, Lisa
Espy, Nicole
Wallis, Carole L
Randhawa, April Kaur
Miner, Maurine D
Ketter, Nzeera
Yacovone, Margaret
Goga, Ameena
Huang, Yunda
Hural, John
Kotze, Philip
Bekker, Linda Gail
Gray, Glenda E
Corey, Lawrence
author_sort Garrett, Nigel
collection PubMed
description We report a 23% asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) Omicron carriage rate in participants being enrolled into a clinical trial in South Africa, 15-fold higher than in trials before Omicron. We also found lower CD4( + )T-cell counts in persons with human immunodeficiency virus (HIV) strongly correlated with increased odds of being SARS-CoV-2 polymerase chain reaction (PCR) positive.
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spelling pubmed-93836232022-08-17 High Asymptomatic Carriage With the Omicron Variant in South Africa Garrett, Nigel Tapley, Asa Andriesen, Jessica Seocharan, Ishen Fisher, Leigh H Bunts, Lisa Espy, Nicole Wallis, Carole L Randhawa, April Kaur Miner, Maurine D Ketter, Nzeera Yacovone, Margaret Goga, Ameena Huang, Yunda Hural, John Kotze, Philip Bekker, Linda Gail Gray, Glenda E Corey, Lawrence Clin Infect Dis Brief Report We report a 23% asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) Omicron carriage rate in participants being enrolled into a clinical trial in South Africa, 15-fold higher than in trials before Omicron. We also found lower CD4( + )T-cell counts in persons with human immunodeficiency virus (HIV) strongly correlated with increased odds of being SARS-CoV-2 polymerase chain reaction (PCR) positive. Oxford University Press 2022-03-30 /pmc/articles/PMC9383623/ /pubmed/35353885 http://dx.doi.org/10.1093/cid/ciac237 Text en © The Author(s) 2022. Published by Oxford University Press for the Infectious Diseases Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Report
Garrett, Nigel
Tapley, Asa
Andriesen, Jessica
Seocharan, Ishen
Fisher, Leigh H
Bunts, Lisa
Espy, Nicole
Wallis, Carole L
Randhawa, April Kaur
Miner, Maurine D
Ketter, Nzeera
Yacovone, Margaret
Goga, Ameena
Huang, Yunda
Hural, John
Kotze, Philip
Bekker, Linda Gail
Gray, Glenda E
Corey, Lawrence
High Asymptomatic Carriage With the Omicron Variant in South Africa
title High Asymptomatic Carriage With the Omicron Variant in South Africa
title_full High Asymptomatic Carriage With the Omicron Variant in South Africa
title_fullStr High Asymptomatic Carriage With the Omicron Variant in South Africa
title_full_unstemmed High Asymptomatic Carriage With the Omicron Variant in South Africa
title_short High Asymptomatic Carriage With the Omicron Variant in South Africa
title_sort high asymptomatic carriage with the omicron variant in south africa
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9383623/
https://www.ncbi.nlm.nih.gov/pubmed/35353885
http://dx.doi.org/10.1093/cid/ciac237
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