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Attenuated HIV-1 Nef But Not Vpu Function in a Cohort of Rwandan Long-Term Survivors

HIV-1 accessory proteins Nef and Vpu enhance viral pathogenesis through partially overlapping immune evasion activities. Attenuated Nef or Vpu functions have been reported in individuals who display slower disease progression, but few studies have assessed the relative impact of these proteins in no...

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Detalles Bibliográficos
Autores principales: Umviligihozo, Gisele, Mann, Jaclyn K., Jin, Steven W., Mwimanzi, Francis M., Hsieh, Hua-Shiuan A., Sudderuddin, Hanwei, Lee, Guinevere Q., Byakwaga, Helen, Muzoora, Conrad, Hunt, Peter W., Martin, Jeff N., Haberer, Jessica E., Karita, Etienne, Allen, Susan, Hunter, Eric, Brumme, Zabrina L., Brockman, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9383652/
https://www.ncbi.nlm.nih.gov/pubmed/35982753
http://dx.doi.org/10.3389/fviro.2022.917902

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