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Lightweight Distributed Provenance Model for Complex Real–world Environments

Provenance is information describing the lineage of an object, such as a dataset or biological material. Since these objects can be passed between organizations, each organization can document only parts of the objects life cycle. As a result, interconnection of distributed provenance parts forms di...

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Autores principales: Wittner, Rudolf, Mascia, Cecilia, Gallo, Matej, Frexia, Francesca, Müller, Heimo, Plass, Markus, Geiger, Jörg, Holub, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9383664/
https://www.ncbi.nlm.nih.gov/pubmed/35977957
http://dx.doi.org/10.1038/s41597-022-01537-6
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author Wittner, Rudolf
Mascia, Cecilia
Gallo, Matej
Frexia, Francesca
Müller, Heimo
Plass, Markus
Geiger, Jörg
Holub, Petr
author_facet Wittner, Rudolf
Mascia, Cecilia
Gallo, Matej
Frexia, Francesca
Müller, Heimo
Plass, Markus
Geiger, Jörg
Holub, Petr
author_sort Wittner, Rudolf
collection PubMed
description Provenance is information describing the lineage of an object, such as a dataset or biological material. Since these objects can be passed between organizations, each organization can document only parts of the objects life cycle. As a result, interconnection of distributed provenance parts forms distributed provenance chains. Dependant on the actual provenance content, complete provenance chains can provide traceability and contribute to reproducibility and FAIRness of research objects. In this paper, we define a lightweight provenance model based on W3C PROV that enables generation of distributed provenance chains in complex, multi-organizational environments. The application of the model is demonstrated with a use case spanning several steps of a real-world research pipeline — starting with the acquisition of a specimen, its processing and storage, histological examination, and the generation/collection of associated data (images, annotations, clinical data), ending with training an AI model for the detection of tumor in the images. The proposed model has become an open conceptual foundation of the currently developed ISO 23494 standard on provenance for biotechnology domain.
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spelling pubmed-93836642022-08-17 Lightweight Distributed Provenance Model for Complex Real–world Environments Wittner, Rudolf Mascia, Cecilia Gallo, Matej Frexia, Francesca Müller, Heimo Plass, Markus Geiger, Jörg Holub, Petr Sci Data Article Provenance is information describing the lineage of an object, such as a dataset or biological material. Since these objects can be passed between organizations, each organization can document only parts of the objects life cycle. As a result, interconnection of distributed provenance parts forms distributed provenance chains. Dependant on the actual provenance content, complete provenance chains can provide traceability and contribute to reproducibility and FAIRness of research objects. In this paper, we define a lightweight provenance model based on W3C PROV that enables generation of distributed provenance chains in complex, multi-organizational environments. The application of the model is demonstrated with a use case spanning several steps of a real-world research pipeline — starting with the acquisition of a specimen, its processing and storage, histological examination, and the generation/collection of associated data (images, annotations, clinical data), ending with training an AI model for the detection of tumor in the images. The proposed model has become an open conceptual foundation of the currently developed ISO 23494 standard on provenance for biotechnology domain. Nature Publishing Group UK 2022-08-17 /pmc/articles/PMC9383664/ /pubmed/35977957 http://dx.doi.org/10.1038/s41597-022-01537-6 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Wittner, Rudolf
Mascia, Cecilia
Gallo, Matej
Frexia, Francesca
Müller, Heimo
Plass, Markus
Geiger, Jörg
Holub, Petr
Lightweight Distributed Provenance Model for Complex Real–world Environments
title Lightweight Distributed Provenance Model for Complex Real–world Environments
title_full Lightweight Distributed Provenance Model for Complex Real–world Environments
title_fullStr Lightweight Distributed Provenance Model for Complex Real–world Environments
title_full_unstemmed Lightweight Distributed Provenance Model for Complex Real–world Environments
title_short Lightweight Distributed Provenance Model for Complex Real–world Environments
title_sort lightweight distributed provenance model for complex real–world environments
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9383664/
https://www.ncbi.nlm.nih.gov/pubmed/35977957
http://dx.doi.org/10.1038/s41597-022-01537-6
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