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Predicting COVID-19 disease severity from SARS-CoV-2 spike protein sequence by mixed effects machine learning

Epidemiological studies show that COVID-19 variants-of-concern, like Delta and Omicron, pose different risks for severe disease, but they typically lack sequence-level information for the virus. Studies which do obtain viral genome sequences are generally limited in time, location, and population sc...

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Detalles Bibliográficos
Autores principales: Sokhansanj, Bahrad A., Rosen, Gail L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9384346/
https://www.ncbi.nlm.nih.gov/pubmed/36041271
http://dx.doi.org/10.1016/j.compbiomed.2022.105969