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SARS-CoV-2 triggers pericyte-mediated cerebral capillary constriction
The SARS-CoV-2 receptor, ACE2, is found on pericytes, contractile cells enwrapping capillaries that regulate brain, heart and kidney blood flow. ACE2 converts vasoconstricting angiotensin II into vasodilating angiotensin-(1-7). In brain slices from hamster, which has an ACE2 sequence similar to huma...
Autores principales: | Hirunpattarasilp, Chanawee, James, Greg, Kwanthongdee, Jaturon, Freitas, Felipe, Huo, Jiandong, Sethi, Huma, Kittler, Josef T, Owens, Raymond J, McCoy, Laura E, Attwell, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9384509/ https://www.ncbi.nlm.nih.gov/pubmed/35867861 http://dx.doi.org/10.1093/brain/awac272 |
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