Combining CRISPR–Cas12a with terminal deoxynucleotidyl transferase dependent reporter elongation for pathogen detection using lateral flow test strips

CRISPR–Cas (CC)-based detection technologies have some exceptional features, which hold the promise of developing into the next-generation diagnostic platforms. One of these features is the ability to trigger non-specific single-stranded DNA/RNA cleavage activity after specific target recognition an...

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Detalles Bibliográficos
Autores principales: Berghuis, Nicole F, Mars-Groenendijk, Roos, Busker, Ruud W, Paauw, Armand, van Leeuwen, Hans C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Methods Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9384837/
https://www.ncbi.nlm.nih.gov/pubmed/35989704
http://dx.doi.org/10.1093/biomethods/bpac015

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