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Co-occurrence of CML Blast Crisis and Severe COVID 19 Infection: A Case Report

Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affecting multiple organ systems. It can cause severe cytokine storms leading to intensive care unit admission requiring mechanical ventilation. However, there have been few studies establis...

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Autores principales: Khaja, Misbahuddin, Hayagreev, Vibha, Haider, Asim, Ronderos, Diana, Siddiqa, Ayesha, Moirangthem, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9384850/
https://www.ncbi.nlm.nih.gov/pubmed/35989789
http://dx.doi.org/10.7759/cureus.26865
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author Khaja, Misbahuddin
Hayagreev, Vibha
Haider, Asim
Ronderos, Diana
Siddiqa, Ayesha
Moirangthem, Valentina
author_facet Khaja, Misbahuddin
Hayagreev, Vibha
Haider, Asim
Ronderos, Diana
Siddiqa, Ayesha
Moirangthem, Valentina
author_sort Khaja, Misbahuddin
collection PubMed
description Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affecting multiple organ systems. It can cause severe cytokine storms leading to intensive care unit admission requiring mechanical ventilation. However, there have been few studies establishing the outcomes of chronic myeloid leukemia (CML) patients on tyrosine kinase inhibitors who are infected with COVID-19. We present a 69-year-old male with a history of CML on imatinib therapy with COVID-19 who developed acute respiratory distress syndrome needing mechanical ventilatory support, shock requiring vasopressors, and worse outcome secondary to blast crisis.
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spelling pubmed-93848502022-08-19 Co-occurrence of CML Blast Crisis and Severe COVID 19 Infection: A Case Report Khaja, Misbahuddin Hayagreev, Vibha Haider, Asim Ronderos, Diana Siddiqa, Ayesha Moirangthem, Valentina Cureus Internal Medicine Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affecting multiple organ systems. It can cause severe cytokine storms leading to intensive care unit admission requiring mechanical ventilation. However, there have been few studies establishing the outcomes of chronic myeloid leukemia (CML) patients on tyrosine kinase inhibitors who are infected with COVID-19. We present a 69-year-old male with a history of CML on imatinib therapy with COVID-19 who developed acute respiratory distress syndrome needing mechanical ventilatory support, shock requiring vasopressors, and worse outcome secondary to blast crisis. Cureus 2022-07-14 /pmc/articles/PMC9384850/ /pubmed/35989789 http://dx.doi.org/10.7759/cureus.26865 Text en Copyright © 2022, Khaja et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Khaja, Misbahuddin
Hayagreev, Vibha
Haider, Asim
Ronderos, Diana
Siddiqa, Ayesha
Moirangthem, Valentina
Co-occurrence of CML Blast Crisis and Severe COVID 19 Infection: A Case Report
title Co-occurrence of CML Blast Crisis and Severe COVID 19 Infection: A Case Report
title_full Co-occurrence of CML Blast Crisis and Severe COVID 19 Infection: A Case Report
title_fullStr Co-occurrence of CML Blast Crisis and Severe COVID 19 Infection: A Case Report
title_full_unstemmed Co-occurrence of CML Blast Crisis and Severe COVID 19 Infection: A Case Report
title_short Co-occurrence of CML Blast Crisis and Severe COVID 19 Infection: A Case Report
title_sort co-occurrence of cml blast crisis and severe covid 19 infection: a case report
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9384850/
https://www.ncbi.nlm.nih.gov/pubmed/35989789
http://dx.doi.org/10.7759/cureus.26865
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