Prospective Clinical Genomic Profiling of Ewing Sarcoma: ERF and FGFR1 Mutations as Recurrent Secondary Alterations of Potential Biologic and Therapeutic Relevance

Ewing sarcoma (ES) is a primitive sarcoma defined by EWSR1-ETS fusions as the primary driver alteration. To better define the landscape of cooperating secondary genetic alterations in ES, we analyzed clinical genomic profiling data of 113 patients with ES, a cohort including more adult patients (>...

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Detalles Bibliográficos
Autores principales: Ogura, Koichi, Elkrief, Arielle, Bowman, Anita S., Koche, Richard P., de Stanchina, Elisa, Benayed, Ryma, Mauguen, Audrey, Mattar, Marissa S., Khodos, Inna, Meyers, Paul A., Healey, John H., Tap, William D., Hameed, Meera, Zehir, Ahmet, Shukla, Neerav, Sawyers, Charles, Bose, Rohit, Slotkin, Emily, Ladanyi, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2022
Materias:
ORIGINAL REPORTS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9384944/
https://www.ncbi.nlm.nih.gov/pubmed/35952322
http://dx.doi.org/10.1200/PO.22.00048

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